Cholestatic liver (dys)function during sepsis and other critical illnesses
نویسندگان
چکیده
منابع مشابه
Mitochondrial dysfunction in cholestatic liver diseases.
Cholestatic liver diseases are characterized by blockade of bile flow from the liver to the intestine, and accumulation of hydrophobic bile acids in the liver and plasma. As a consequence an inflammatory response evolves associated with increased apoptosis, oxidative stress, and eventually fibrosis. Cholestasis is associated with profound metabolic changes, alterations in the mitochondrial func...
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ژورنال
عنوان ژورنال: Intensive Care Medicine
سال: 2015
ISSN: 0342-4642,1432-1238
DOI: 10.1007/s00134-015-4054-0